Management of nonfunctioning pituitary incidentaloma

Pituitary incidentaloma.

All patients with pituitary incidentaloma should be investigated for pituitary hyperfunction. The single most important test is measurement of serum prolactin (PRL). Elevated PRL can indicate either direct tumour secretion (levels are typically 800–2,000 mU/l for microprolactinoma, >2,000 mU/l for macroprolactinoma and <600 normally) or ‘disconnection’ of the hypothalamus and normal pituitary g...

Acromegaloidism Associated with Pituitary Incidentaloma.

Acromegaloidism with pituitary microadenoma has not been previously reported. We present a case of a 28-year old male with typical features of acromegaly for 11 years.with a pituitary tumor. He had characteristic acromegaloid facial features, clubbing of hands and feet, enlargement of fingers and toes. The natural history of the disease is reviewed and the differential diagnosis is discussed.

A survey of pituitary incidentaloma in Japan.

OBJECTIVE The development of computed tomography (CT) and magnetic resonance imaging (MRI) has resulted in the discovery of unsuspected endocrinologically silent pituitary masses (pituitary incidentalomas). The aim of this study was to perform a national survey on pituitary incidentalomas in order to establish an appropriate approach to them. DESIGN AND METHODS Five hundred and six patients w...

Nonfunctioning giant pituitary adenomas: Invasiveness and recurrence

BACKGROUND We report our surgical series of 35 patients with giant nonfunctioning pituitary adenomas (GNFPA). We analyzed the rule of Ki-67 antigen expression in predicting recurrence. METHODS Thirty-five patients were operated between 2000 and 2010. Suprassellar extension of the tumors were classified according to Hardy and Mohr based on magnetic resonance (MR) studies. Pituitary endocrine f...

Pituitary “incidentaloma”: Neuroradiological assessment and differential diagnosis